<strong>Optimisation of an esterification reaction</strong></br>Case Study

Optimisation of an esterification reaction
Case Study

Specialty Chemicals, Fine Chemicals
PROJECT DESCRIPTION Our client produces polymers by polyesterification on several sites all over the world. He wants to reduce esterification time by optimizing mixing of reactants and distillation of light products. This has to be done for each site. PROJECT METHODOLOGY Processium diagnoses the hydrodynamics regime of each reactor. Based on hydrodynamics regime and impeller design, Processium proposes other impellers. A sizing of each new impeller is proposed. Solutions are compared and ranked. A new impeller and its sizing is chosen with the client. Distillation mode are not the same, depending on the site. Especially, regulation mode are not the same. Processium proposes a standard of regulation mode to ensure process robustness. A new packing is also proposed, to ensure distillate quality. RESULTS The process is optimized via change of impellers…
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<strong>Solvent substitution in a coating formulation</strong></br>Case Study

Solvent substitution in a coating formulation
Case Study

Paints and Coatings
PROJECT DESCRIPTION Our client need to replace its solvents in his coating formulation due to legislative changes. The alternative solvents have to keep the same physico-chemical properties of the formulation, or even is feasible to improve them in order to keep a competitive advantage on the market. The project deals with many technical challenges: Prediction of physico-chemicals properties on a mixture of solvent rather than on pure solvent. Take into account interaction between solvents and polymers Definition of solvent key properties in the final mixture. OUR METHODOLOGY For the research of alternative solvents mixtures, Processium has: Characterized the client products: our expertise in modelling ensures a reliable prediction of key properties for the different solvents (viscosity, evaporation rate…) Defined the specifications of the new solvent mixture (performance at least equal to…
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<strong>Processium is Moving !!!</strong></br>News

Processium is Moving !!!
News

news-processium-
Founded in 2002 by engineers coming from the chemical industry, Processium is an independent company employing about forty collaborators and specialized in design, development and optimisation of processes for chemical and biotechnological industries. Processium provides services for the biggest industrial companies and also supports the industrialisation of projects coming from innovative start-up.   Processium has high-level team of experts, laboratories dedicated to analysis, measurements and laboratory scale pilot units. Processium participates actively, in particular within the framework of collaborative research projects, in miscellaneous European technical and business clusters and associations.   Processium has created in 2014 a subsidiary located on the scientific campus of Unicamp (São Paulo State, Brazil), and strengthens its commercial presence in Europe and in North America. To come along with this development, Processium is moving into…
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<strong>DEINOVE announces the success of its cosmetic active ingredient’s production process industrialization</strong></br>News

DEINOVE announces the success of its cosmetic active ingredient’s production process industrialization
News

news-processium
  DEINOVE (Euronext Growth Paris: ALDEI), a biotech company that discovers, develops, and produces high-value compounds from rare bacteria, notably from the Deinococcus genus, announces having produced the first industrial batch of its innovative carotenoid. As announced in December, the scale-up of the fermentation production process was carried out on the technological platform of the BIOGIS Center at SAS PIVERT. After a technology transfer stage, a first production of several cubic meters was successfully completed. The biomass produced followed an original and environmentally-friendly process, developed in collaboration with PROCESSIUM, for extraction, purification, and formulation, resulting in the first industrial batch of the end product. DEINOVE selected VEG’EXTRA, a specialist in extraction, as a provider for these downstream processing steps. Read more ...
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<strong>Deinove launches the industrial production of its first carotenoid</strong></br>News

Deinove launches the industrial production of its first carotenoid
News

news-processium
  DEINOVE (Euronext Growth Paris: ALDEI), a biotech company that discovers, develops, and produces high-value compounds from rare bacteria, notably from the Deinococcus genus, announces the launch of the industrial production of its first carotenoid. The company's fermentation platform has developed an optimized process in terms of performance and robustness on a 20-liter scale. At the same time, the collaboration with Processium lead to the definition of the downstream process of extraction, purification, and formulation, and the drafting of the "Process Book" detailing its implementation. Read more ...
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<strong>Measurements of density, heat capacity, viscosity and thermal conductivity on heat transfer fluids up to 250°C</strong></br>Case Study

Measurements of density, heat capacity, viscosity and thermal conductivity on heat transfer fluids up to 250°C
Case Study

Specialty Chemicals, Oil and Gas, Fine Chemicals
  PROJECT DESCRIPTION Our customer wishes to characterize thermophysical properties (heat capacity, vapour pressure, viscosity, density, thermal conductivity, etc.) of new heat transfer fluids used in a wide range of temperatures. TECHNICAL CHALLENGES Our teams of experts conducted tests on the fluids with in mind the temperature dependence of each property in order to optimise the number of experimental points to reduce the cost for the client. RESULTS A complete mapping of physical properties to provide technical datasheet of each thermal fluid.
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<strong>Deactivation test on catalysts</strong></br>Case Study

Deactivation test on catalysts
Case Study

Industrial Biotechnlogy, Specialty Chemicals, Oil and Gas, Natural Ingredients, Fine Chemicals
  PROJECT DESCRIPTION Our customer wishes to know the kinetic of deactivation of its catalyst under industrial conditions in order to adapt the sizing of corresponding process accordingly. In addition to this, the definition of the frequency of replacement of the catalyst was also an issue to secure productivity. TECHNICAL CHALLENGES Test should be performed continuously over hundreds of hours on a reactive mixture under conditions which precisely represent the operating conditions (temperatures over 250°C and pressures of 6 bar). The test needed to implement a dedicated bench to test the catalyst in continuous mode. OUR METHODOLOGY Design and development of a continuous reaction bench equipped with a tubular reactor working in conditions close to those of the process (6 bar and 250°C). Regular sampling from the reactor for 30 days.…
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<strong>DEINOVE: the industrialization process of the carotenoids program enters Phase II</strong></br>News

DEINOVE: the industrialization process of the carotenoids program enters Phase II
News

News
  In November 2016, DEINOVE launched the shift from laboratory to industrial scale, accompanied by the company Processium* . The first phase of this program consisted of: Selecting and characterizing a first carotenoid that will be market-ready, validating both its biological properties and its economic potential; Optimizing the production strain and increasing the yields in the laboratory, with a view to obtaining a strain suitable for industrial production; Evaluating the various extraction processes in order to define the best one in industrial production conditions. This phase I has been conducted successfully. A first molecule has been selected for its innovative feature, with the goal of obtaining a competitive advantage on the market. DEINOVE has demonstrated its total safety, but also its antioxidant and healing properties, which position this first molecule…
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<strong>Debottlenecking of batch process</strong></br>Case Study

Debottlenecking of batch process
Case Study

Specialty Chemicals
PROJECT DESCRIPTION The Client produces ester in a batch process (reaction + distillation column). Processium services were requested to enhance unit productivity by decreasing the duration of each batch. Improvement of co-product quality is also requested and part of the Project. OUR METHODOLOGY The first task issued by Processium was a statistical study on process data issued from SNCC to identify the reasons for dysfunction among all parameters (quality of reactants, temperature, stoechiometry, …). This study highlighted several parameters responsible of malfunctions of the unit. Thanks to the management of these identified parameters during production, productivity increased of 5%. Following this first study, Processium conducted a new study based on kinetics and thermodynamics measurements, development of corresponding models and process optimization using ASPEN simulation. RESULTS Unit had been debottlenecked (10%) without…
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<strong>Odour removal</strong></br>Case Study

Odour removal
Case Study

Specialty Chemicals
PROJECT DESCRIPTION The Client uses distillation to purify an added value product. One of the impurity is an odorous molecule that causes two limitations: the product can not be supplied for specific application because of the smell given to the product by the odorous impurity, in order to limit the quantity of odorous impurity in the product, the yield of purification has to remain low. The Client asks to Processium to identify a technical solution to retain the odorous impurity  in the bottom of the distillation column. OUR METHODOLOGY To be able to propose technical solutions, Processium developed the following methodology: identification of a technical solution (bibliography, internal know-how), screening of existing activated carbons using in-house database including exhaustive data on possible suppliers, development of a design of experiments to minimize…
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